Coming soon

30. "Single-molecule imaging in the primary cilium," LE Weiss, JF Love, J Yoon, CJ Comerci, T Kanie, PK Jackson, T Stearns, & A-K Gustavsson. Methods in Cell Biology, Academic Press (Accepted).


29. "THY1-mediated mechanisms converge to drive YAP activation in skin homeostasis and repair," E Sedov, E Koren, S Chopra, R Ankawa, Y Yosefzon, M Yusupova, LE Weiss, A Mahly, A Soffer, A Feldman, C Luxenburg, Y Shechtman, & Y Fuchs. Nature Cell Biology (2022). (

28. "Synthetic cells with self-activating optogenetic proteins communicate with natural cells," O Adir, MR Albalak, R Abel, LE Weiss, G Chen, A Gruber, O Staufer, Y Kurman, I Kaminer, J Shklover, J Shainsky-Roitman, I Platzman, L Gepstein, Y Shechtman, BA Horwitz, A Schroeder. Nature Communications (2022). (

27. "Quantifying cell cycle dependent chromatin dynamics during interphase by live 3D tracking," T Naor, Y Nogin, E Nehme, B Ferdman, LE Weiss, O Alalouf, Y Shechtman. iScience (2022). (

  • 26. "High-throughput Imaging of CRISPR- and Recombinant Adeno-associated Virus–induced DNA Damage Response in Human Hematopoietic Stem and Progenitor Cells" D Allen*, LE Weiss*, A Saguy, M Rosenberg, O Iancu, O Matalon, C Lee, K Beider, A Nagler, Y Shechtman, and A Hendel. The CRISPR Journal (2022). *Equal Contribution (;

25. "Multiplexed PSF engineering for 3D multicolor particle tracking," N Opatovski, Y Shalev Ezra, LE Weiss, B Ferdman, R Orange, Y Shechtman. Nanoletters (2021). (

24. "Learning optimal wavefront shaping for multi-channel imaging," E Nehme*, B Ferdman*, LE Weiss, T Naor, D Freedman, T Michaeli, Y Shechtman. IEEE Transactions on Pattern Analysis and Machine Intelligence (2021). *Equal Contribution (;

23. "Automated analysis of fluorescence kinetics in single-molecule localization microscopy data reveals protein stoichiometry," A Saguy, T Baldering, LE Weiss, E Nehme, C Karathanasis, M Dietz, M Heilemann, Y Shechtman. The Journal of Physical Chemistry B (2021). (;

22. "3D Printable diffractive optical elements by liquid immersion," R Orange, E Nehme, LE Weiss, N Opatovski, B Ferdman, O Alalouf, Y Shechtman. Nature Communications (2021). ( );

21. "Microscopic scan-free profilometry by PSF engineering," R Gordon, LE Weiss, B Ferdman, E Nehme, R Eshel, M Bercovici, Y Shechtman. Science Advances (2020). (;

20. "DeepSTORM3D: dense 3D localization microscopy and PSF design by deep learning," E Nehme, D Freedman, R Gordon, B Ferdman, LE Weiss, O Alalouf, R Orange, T Michaeli, Y Shechtman. Nature Methods (2020). (;

  • 19. "Three-dimensional localization microscopy in live flowing cells," LE Weiss, Y Shalev Ezra, SE Goldberg, B Ferdman, O Adir, A Schroeder, O Alalouf, Y Shechtman. Nature Nanotechnology (2020). (;

"Single-molecule imaging goes high throughput," J Enderlein, Nature Nanotechnology: News & Views (2020). (
"Go with the flow: high throughput 3D localization in cells by depth-encoding imaging flow cytometry,"
LE Weiss, Bioengineering Community (2020). (link)

18. "VIPR: Vectorial Implementation of Phase Retrieval for fast and accurate microscopic pixel-wise pupil estimation," B Ferdman, E Nehme, LE Weiss, R Orange, O Alalouf, Y Shechtman. Optics Express (2020). (;

Editor's Pick, Optics Express

17. "Single particle diffusion characterization by deep learning," N Granik, LE Weiss, E. Nehme, M Shalom, M Chein, E Perlson, Y Roichman, Y Shechtman. Biophys. J., 117(2), 1-8 (2019). (;

  • 16. "Multicolor localization microscopy and point-spread-function engineering by deep learning," E Hershko*, LE Weiss*, T Michaeli, Y Shechtman. Optics Express, 27(5), 6158-6183 (2019). *Equal Contribution (;

  • 15. "Motional dynamics of single Patched1 molecules in cilia are controlled by Hedgehog and cholesterol," LE Weiss*, L Milenkovic*, J Yoon, T Stearns, WE Moerner. Proc. Natl. Acad. Sci. U.S.A.,116 (12) 5550-5557 (2019). *Equal Contribution (;

14. "Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopy," J Yoon, CJ Comerci, LE Weiss, L Milenkovic, T Stearns, WE Moerner, Biophys. J., 116(2) (2019). (;

Issue cover, Biophysical Journal

  • 13. "Ultrasensitive refractometry via supercritical angle fluorescence," B Ferdman* LE Weiss*, O Alalouf, Y Haimovich, Y Shechtman. ACS Nano, 12(12), 11892–11898 (2018). *Equal Contribution (;

  • 12. "Observing DNA in live cells," LE Weiss, T Noar, Y Shechtman. Biochemical Society Transactions, 46(3), 629-740 (2018). (;

11. "Deep-STORM: Super resolution single molecule microscopy by deep learning," E Nehme, LE Weiss, T Michaeli, Y Shechtman. Optica, 5(4), 458-464 (2018). (;

"Deep learning advances super-resolution imaging," R Strack, Nature Methods, 15, 403 (2018)
Most read paper of the year, Optica

10. "Experimental demonstration of sparsity-based single-shot fluorescence imaging at sub-wavelength resolution," M Mutzafi, Y Shechtman, O Dicker, LE Weiss, YC Eldar, WE Moerner. CLEO: Applications and Technology, AW1A. 6 (2017). (;

9. "Multicolour localization microscopy by point-spread-function engineering," Y Shechtman, LE Weiss, AS Backer, M Lee, & WE Moerner. Nat. Phot., 137, 1-5 (2016). (;

"Simultaneous multicolor localization microscopy," R Strack. Nature Methods 13, 814 (2016). (

8. "Delayed emergence of subdiffraction-sized mutant Huntingtin fibrils following inclusion body formation," SJ Sahl, LLau, WIM. Vonk, LE Weiss, J Frydman & WE Moerner. Q. Rev. Biophys. (2015). (;

  • 7. "Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1," L Milenkovic*, LE Weiss*, J Yoon, TL Roth, YS Su, SJ Sahl, MP Scott, WE Moerner. Proc. Natl. Acad. Sci. USA, 112, 8320-8325 (2015). *Equal Contribution (;

Highlighted in Science.

6. "Precise 3D scan-free multiple-particle tracking over large axial ranges with tetrapod point spread functions," Y Shechtman, LE Weiss, AS Backer, SJ Sahl, WE Moerner. Nano Lett., 15(6), 4194-4199 (2015). (;

5. "Robust hypothesis tests for detecting statistical evidence of two-dimensional and three-dimensional interactions in single-molecule measurements," CP Calderon, LE Weiss, WE Moerner. Phys. Rev. E., 89, 52705-52712 (2014). (;

  • 4. "Cellular inclusion bodies of mutant Huntingtin exon1 obscure small fibrillar aggregate species," SJ Sahl*, LE Weiss*, WC Duim, J Frydman, WE Moerner. Sci. Rep., 2, 895 (2012). *Equal Contribution (;

3. "Flexible electrical recording from cells using nanowire transistor arrays," T Cohen-Karni, BP Timko, LE Weiss, CM Lieber. Proc. Natl. Acad. Sci. USA, 106, 7309-7313 (2009). (;

  • 2. "Engineering motility as a phenotypic response to LuxI/R-dependent quorum sensing in Escherichia coli," LE Weiss, JP Badalamenti, LJ Weaver, AR Tascone, TL Richard, PS Weiss, PC Cirino. Biotech. & Bioeng., 100, 1251-1255 (2008). (;

Highlighted in Biotechnology Journal.

1. "Synthetic sports: A bacterial relay race," JP Badalamenti, LE Weiss, CJ Buckno, TL Richard, PS Weiss, PC Cirino. IET Syn. Bio., 1.2, 61-63 (2007). (;